What is the function of Rutin?

1、 Character

Rutin, also known as rutin or vitamin P, has a molecular formula of

CorHlso016 is a natural flavonoid glycoside that belongs to the flavonol glycosides widely present in plants. The two glycosides are glucose and xylose. The appearance is a light yellow or light green crystalline powder. It is soluble in pyridine, formyl, and alkaline solutions, slightly soluble in ethanol, acetone, and ethyl acetate, and almost insoluble in chloroform, ether, benzene, carbon disulfide, and petroleum ether.

2、 Source

Widely present in the roots, stems, leaves, flowers, fruits, and seeds of plants such as Rutaceae, tobacco, buckwheat, and Sophora japonica L., the content is relatively high in the flower buds of Sophora japonica L., reaching more than 20%. China is the origin of Sophora japonica L., and 98% of the world's Sophora japonica comes from China. Therefore, Sophora japonica L. is often used as a raw material for industrial extraction of rutin in China.

3、 Anti cancer and anti-tumor

Research has found that flavonoids mainly exert anti-cancer and anti-tumor effects through three pathways, namely anti free radical effects, direct inhibition of cancer cell growth, and anti carcinogenic factors. Flavonoids can make cancer cells sensitive to anticancer drugs and improve drug resistance in patients receiving cancer treatment. Numerous studies have shown that this antioxidant can reduce tumor size, increase cancer cell death, and prolong survival time.

4、 Anti cardiovascular and cerebrovascular diseases

Rutin can promote capillary blood circulation in the human body, increase sensitivity to insulin, reduce vascular fragility, decrease vascular permeability, and prevent hypertension. At the same time, rutin can inhibit platelet aggregation and thrombus formation, reduce the risk of thrombosis, and have a certain protective effect on preventing cardiovascular and cerebrovascular diseases.

5、 Anti inflammatory and analgesic effects

Rutin has a certain anti-inflammatory effect, which can inhibit the production of inflammatory factors and alleviate inflammatory reactions. It is commonly used to treat inflammatory diseases such as rheumatoid arthritis and hepatitis.

6、 Protecting the liver

Rutin can also protect the liver, alleviate liver damage caused by various reasons, and promote the repair of damaged tissues.

7、 Anti gasification and anti-aging

Rutin can enhance the activity of vitamin C, have antioxidant effects, and resist the erosion of free radicals. At the same time, it can address the unique symptoms of hot flashes in menopausal women. Rutin has a strong absorption effect on ultraviolet rays and X-rays, making it a natural sunscreen and one of the choices for beauty conscious women. Nowadays, many sunscreen products add rutin ingredients.

8、 Clinical application

Rutin and its derivatives have a wide range of pharmacological activities. They are commonly used clinically to prevent and treat cerebral hemorrhage, hypertension, retinal hemorrhage, purple scar, acute hemorrhagic nephritis, chronic tracheitis, vascular fragility, abnormal vascular osmotic pressure and other diseases, prevent and treat diabetes and hyperlipidemia, and protect the heart, kidney, brain and other organs from ischemia-reperfusion injury. The total effective rate of its treatment for chronic bronchitis is 84.4%. Toxenutin, a derivative of rutin, is widely used in clinical practice to treat burns, arthritis, and various vascular diseases.

9、 Conclusion

Rutin, as an important traditional Chinese medicine compound, has strong pharmacological activity, low toxicity, and is widely present in plants. With the rapid development of medicinal chemistry and modern formulation technology, significant achievements have been made in recent years in the research of rutin, the discovery of new resources, the improvement of extraction processes, the depth and breadth of pharmacological research, as well as chemical research and application. Based on clarifying the structure-activity relationship, this compound is used as a lead compound for structural optimization, making its pharmacological effects more targeted and efficient. However, the research on rutin metal complexes is not yet in-depth enough. Therefore, strengthening the research on rutin metal complexes, determining the molecular structure and spatial configuration of rutin metal complexes, selectively screening metal elements, and combining them with pharmacological research can be used as a direction for rutin drug research.

For more information,pls contact sales@andybiotech.com