A New Generation Of Wolfberry Powder Rich In Wolfberry Acid
A New Generation Of Wolfberry Powder Rich In Wolfberry Acid
Goji berries have always been a national tonic, favored for their functions such as nourishing the liver and kidney, benefiting the essence and eyesight, nourishing blood, and enhancing people's immunity. Modern pharmacological research has shown that goji berry polysaccharides in goji berries have effects such as improving immunity, anti-aging, anti-tumor, clearing free radicals, anti-fatigue, anti-radiation, protecting the liver, protecting and improving reproductive function.
However, another natural active ingredient in goji berries - goji acid( β— Ascorbic acid glucoside, AA-2 β G) It has been neglected and has not received effective attention and development application. Lycium barbarum acid is a new stable VC (L-ascorbic acid) derivative discovered from Lycium barbarum. Existing in vivo and in vitro experimental studies have shown that wolfberry acid has certain free radical scavenging and antioxidant abilities. Moreover, compared to L-ascorbic acid, the antioxidant effect of wolfberry acid is more gentle and long-lasting, and its antioxidant activity is also higher.
↓ Natural stable L-ascorbic acid derivative
Lycium barbarum acid can be directly absorbed by the intestinal tract, enter the blood β— The hydrolysis of glucosidase releases L-ascorbic acid, which plays a role in scavenging free radicals and antioxidant activity
↓ The antioxidant effect of wolfberry acid
The results of in vitro antioxidant experiments such as DPPH method, ABTS method, ORAC method, and APPH induced inhibition of red blood cell hemolysis test showed that the antioxidant activity of Lycium barbarum acid was significantly higher than that of L-ascorbic acid and a-ascorbic acid glucoside, and the time for scavenging free radicals was longer, achieving the effect of L-ascorbic acid sustained release.
The results of in vitro antioxidant experiments indicate that compared with L-ascorbic acid, wolfberry acid has a stronger ability to clear DPPH and hydrogen peroxide, and can control the hemolysis caused by hydrogen peroxide; Meanwhile, wolfberry acid has the same ability to scavenge hydroxyl radicals as L-ascorbic acid; However, wolfberry acid does not have the ability to scavenge superoxide anions, and its ability to scavenge nitrite is weaker than L-ascorbic acid. Further in vivo antioxidant experiments showed that Lycium barbarum acid could protect the liver of mice from acute liver injury caused by carbon tetrachloride, and significantly reduce the levels of glutamic transaminase and glutamic transaminase in serum.
↓ The hypoglycemic effect of wolfberry acid
Lycium barbarum acid has significant competitive inhibitory activity on yeast derived a-glucosidase. The results of in vitro enzyme inhibition activity experiments showed that the inhibitory rate of Lycium barbarum acid on a-glucosidase was positively correlated with its concentration. Its IC50 value (0.98 mmol/L) was lower than that of Acarbose (4.54 mmol/L), indicating that Lycium barbarum acid has a higher inhibitory ability than Acarbose and has the potential to develop hypoglycemic drugs.
Other studies have shown that Lycium barbarum acid combines the three main amino acid active site of the a-glucosidase from Saccharomyces cerevisiae, ASP214, GLU276 and ASP349, and competitively inhibits the activity of a-glucosidase. In vivo experiments in mice also showed that Lycium barbarum acid could improve postprandial blood glucose in normal mice and diabetes mice. Feeding normal mice with starch with gojic acid resulted in a blood glucose increase rate of only 20% at 30 minutes and returning to fasting blood glucose levels after 120 minutes; The diabetes model mice taking maltose were fed with Lycium barbarum acid, and the blood glucose rise rate was only 10% at 30 minutes, and fell to the fasting blood glucose level after 80 minutes; The diabetes model mice taking starch were fed with Lycium barbarum acid. The rate of blood glucose rise was 18% in 30 minutes and fell to the fasting blood glucose level in 60 minutes. Therefore, wolfberry acid can effectively control postprandial blood sugar levels
↓ Goji berry powder - a new generation of goji berry powder rich in goji berry acid
Lycium barbarum powder is a new generation of Lycium barbarum powder product developed by Shanghai Nord Biological Industry Co., Ltd. after nearly ten years of research and independent development. It is rich in Lycium barbarum acid.
The content of goji berry acid in this product can reach over 3.0%, and no excipients are added. The true goji berry polysaccharide content is also much higher than the common goji berry powder on the market, about 2-3 times.
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