History of Olive leaf extract

A French army colonel, Yitian Palas, M.D., analyzed the composition of the leaves and isolated a crystallizable substance he named Brucine, a bitter substance that he considered to have strong antipyretic properties. This is also considered to be the beginning of modern research on olive leaf extract. Olive leaf extract is a broad-spectrum antibacterial component taken orally. The most active substance identified in olive leaves is oleopicroside, a class of bitter monoglycosides classified as schizoiridoids. Oleopicroside and its hydrolysates have unique significance for the antibacterial function of olive leaves

As a symbol of peace, stability and abundance, the olive tree provided food and shelter for mankind as early as the beginning of human history. It is generally believed that it originated along the Mediterranean coast more than 5000 years ago and was first brought to the United States in the 15th century. There are signs that drinking tea made from olive leaves is a centuries old traditional treatment for discomfort such as cough, sore throat, cystitis and fever in the Middle East. In addition, olive leaf ointment is used to treat boils, rashes, warts and other skin diseases. It was not until the early 18th century that olive leaves began to attract the attention of medical institutions

Function

Olive leaf extract has a full effect on infectious and malignant microorganisms. It can stop the attack of cold and other viral diseases, fungus, mold and yeast invasion, mild and severe bacterial infection and protoparasite infection. Not only preventive, olive leaf extract provides a safe and effective treatment in the fight against microorganisms. The study also proved that the extract only attacks pathogens and is harmless to symbiotic intestinal bacteria in human body, which is another advantage over artificial antibiotics.

Antioxidation

Oleopicroside can protect skin cells from UV damage, prevent the decomposition of skin membrane lipids by UV, promote the production of collagen protein by fiber cells, reduce the secretion of collagen enzyme of fiber cells, and prevent the anti glycan reaction of cell membrane, so as to highly protect fiber cells, naturally resist the damage of skin caused by oxidation, and avoid UV damage, effectively maintain skin tenderness and elasticity, and achieve skin strengthening The effect of rejuvenation.

Strengthening the immune system

Some doctors have successfully used olive leaf extract in the treatment of patients with medically unexplained diseases such as chronic fatigue syndrome and myofibrodyne. This may be the result of its direct stimulation of the immune system.

Cardiovascular disease

Some cardiovascular diseases have also received good response after using olive leaf extract. Coronary heart disease appears to have received a good response after treatment with olive leaf extract. According to laboratory and preliminary clinical studies, olive leaf extract can reduce the discomfort caused by insufficient arterial flow, including angina pectoris and intermittent claudication. It helps to eliminate atrial fibrillation (arrhythmia), reduce hypertension and inhibit the production of LDL cholesterol by oxidation

Safety

The researchers tested the toxicity of oleopicroside by continuously supplying albino mice with an ultra-high dose of 1G / kg for 7 days. No deaths occurred, and the high dose did not cause any toxicological effects. In fact, the high safety of oleopicroside in olive leaf extract even prevented investigators from successfully determining its lethal dose.

Use area of Olive leaf extract

a.medicine

It is used to manufacture new drugs for treating diseases caused by viruses, bacteria, protozoa, parasites and blood sucking insects, and new drugs for treating colds.

b.Health Food

In Europe, America and other countries, olive leaf extract is mainly used as a dietary supplement to regulate immunity.

c.skin care products

The high content of oleopicroside is mainly used in skin care products, which can protect skin cells from UV damage, effectively maintain skin tenderness and elasticity, and achieve the effect of strengthening and rejuvenating skin. Microherb's high content of 80% oleopicroside is specially designed for skin care products. With high effective ingredients and light color, it is very suitable for cosmetic formula design.

Olive leaf essence applied to skin care products has protective, antioxidant and repairing effects.

1. Protection - antioxidation - maintain the viability of skin cells

Ultraviolet rays can cause the formation of free radicals, which can damage skin cells and even cause cell death in the morning. Suppose that skin cells are exposed to light, and then look at the changes in keratinocytes and fibroblasts. Some are coated with pure olive leaf extract and others are not coated. After 24 hours, the cells are observed. The cells that are coated with pure olive essence essence are almost intact.

2. Protective antioxidant reaction

Ultraviolet light can also cause the breakdown of cell membrane lipids. This imagination is peroxidation. The remaining culture environment of skin fibroblasts is coated with pure olive leaf essence and others are not. After that, fluorescence analysis measures a special substance secreted during decomposition to measure the degree of peroxidation. The experiment proved that the pure olive leaf essence can effectively organize the peroxidation reaction and thus highly protect the fibroblasts.

3. Repair - promote collagen metabolism - promote collagen synthesis. In the process of skin aging, the ability of collagen synthesis gradually decreases, and fiber cells can only produce a small amount of collagen. In the cell culture environment, we measured the extent of the synthesis of GF, some of which were added to the pure olive leaf essence, and others did not use proline (an amino acid) as the indicator of the new synthetic GF protein. Experiments showed that olive leaf essence could significantly promote fibroblast production of collagen protein.

4. Anti glycan reaction glycan reaction is a reaction that occurs in the cell membrane. It will cause the network of collagen, so that the collagen protein loses its original elasticity, and the skin will appear depression, that is, wrinkles. This phenomenon increases with age. After 8 days of incubation in 37C tube, the derivative of glycan reaction - formed between lysine and glucose-6-phosphate (ester) enzyme - was tracked by fluorescence analysis. The experiment also showed that it was important to the anti glycan reaction by adding pure olive leaf essence and no pure olive leaf essence.

5. Anti collagenase collagenase is an enzyme produced by fiber cells under the influence of free radicals - under ultraviolet irradiation, keratinocytes will release some information, thus stimulating fiber cells to produce collagenase. Olive leaf essence was added to keratinocyte culture medium and irradiated with UVA and UVB. Before and after the sampling, the results showed that the essence of olive leaf extract indirectly reduced the secretion of colloid enzymes by inhibiting the generation of "information" of keratinocytes caused by ultraviolet light